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Arizona Cardinals’ offensive line rebuild sparks memories of 2021 NFL season

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© Michael Chow/The Republic / USA TODAY NETWORK

GLENDALE – For most of their modern history in the NFL, the Arizona Cardinals have tried to solve offense from the outside in. Find the quarterback, add weapons, although addressing the talent on the offensive line has never been a sticking point for the franchise. This offseason suggests a reversal.

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Arizona’s signing of veteran guard Isaac Seumalo represents more than a roster addition; it signals structural investment. The 6-foot-4, 303-pound lineman arrives with a decade of experience, a Super Bowl ring, and 60 career starts, including 44 over the last three seasons in Pittsburgh. Slotting next to Paris Johnson Jr. on the left side, Seumalo instantly gives the Arizona Cardinals something it has lacked for years: stability at the point of attack.

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Dec 25, 2024; Pittsburgh, Pennsylvania, USA; Pittsburgh Steelers guard Isaac Seumalo (73) at the line of scrimmage against the Pittsburgh Steelers during the second quarter during the second quarter at Acrisure Stadium. Mandatory Credit: Charles LeClaire-Imagn Images

The Cardinals didn’t stop there. Depth additions Matt Pryor and Elijah Wilkinson add flexibility across the line, while the release of Evan Brown signals a deliberate reshaping of the unit. Pryor brings 109 games of experience and positional versatility, while Wilkinson, after a breakout 2025 season in Atlanta, returns to Arizona with the profile of a capable starter rather than emergency depth.

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Nov 16, 2025; Atlanta, Georgia, USA; Atlanta Falcons offensive lineman Elijah Wilkinson (71) defends Carolina Panthers outside linebacker Nic Scourton (11) in the second quarter at Mercedes-Benz Stadium. Mandatory Credit: Brett Davis-Imagn Images

For Arizona Cardinals fans, the blueprint feels familiar. The last time Arizona made a concerted investment in the offensive line was 2021. That unit that featured D.J. Humphries, Justin Pugh, Rodney Hudson, and Kelvin Beachum, powered a balanced offense that opened the season 10–2 before injuries unraveled the run. The lesson from that season wasn’t just about health. It was about infrastructure.

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Sep 18, 2022; Paradise, Nevada, USA; A general overall view of the helmets at the line of scrimmage as Arizona Cardinals center Rodney Hudson (61) snaps the ball against the Las Vegas Raiders Allegiant Stadium. Mandatory Credit: Kirby Lee-USA TODAY Sports

Quarterback uncertainty still hovers over Arizona’s roster following the release of Kyler Murray. But the Cardinals appear to be betting that stability up front will raise the floor of the offense regardless of who takes the snaps. For a franchise that has rarely built from the trenches outward, this shift could redefine the next era of Cardinals football. If the 2021 NFL season taught the Arizona Cardinals anything, it’s that when they protect the pocket, everything else tends to follow.

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Reporter Benjamin Bliklen covers the Arizona Diamondbacks, Arizona Cardinals, and Phoenix Suns for Burn City Sports. You can follow him on his X account, @BenBliklen

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