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Cardinals’ Calais Campbell gets honest on who he wants the 49ers to start at QB

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Syndication: Arizona Republic

GLENDALE – The San Francisco 49ers are trying to keep the Arizona Cardinals on their toes ahead of the teams’ Week 3 matchup. The 49ers claim that QB Brock Purdy still has a chance to play on Sunday, but it is a longshot. If he isn’t able to suit up, last week’s starter Mac Jones will make his second start for San Francisco. The confusion on who will start could be a tactic against Arizona to have them prepare for both QBs across the week.

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Cardinals players have been asked on which QB they would rather face, with most of them giving coachspeak answers of they don’t care who they face. However, 39-year-old Calais Campbell didn’t hold back in his answer to the question.

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Sep 14, 2025; Glendale, Arizona, USA; Arizona Cardinals defensive tackle Calais Campbell (93) walks off the field after the win against the Carolina Panthers at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

Cardinals’ Campbell on who he would rather play:

Campbell does show respect to Jones, calling him a first-round talent. Jones has been thrusted into the starting role after Purdy suffered an injury in Week 1. The former Pro Bowler had a masterful performance in Week 2, throwing for 279 passing yards and three touchdowns.

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Sep 14, 2025; New Orleans, Louisiana, USA; San Francisco 49ers quarterback Mac Jones (10) looks to pass against the New Orleans Saints during the first half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

The fifth-year pro is still a starting-caliber QB in this league, and Campbell understands that Arizona can’t treat him lightly. However, this is only Jones second week as the starter for San Francisco and it could be the moment for growing pains for the 27-year-old.

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Reporter Tanner Tortorella covers general assignment for Burn City Sports. You can follow him on his X account, @TannerTSports

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