GLENDALE – It seems like every day a new name for the Arizona Cardinals is added to the injury report, and Thursday was no different. The team released its injury report for Sunday’s Week 11 game vs. the San Francisco 49ers following Thursday’s practice. The list included 18 names, with seven of those names being DNP. Some names were expected, Marvin Harrison Jr. having appendicitis and Will Johnson with a back injury.
Thank you for reading this post, don't forget to subscribe!However, a new name appeared in the form of edge Josh Sweat. The 28-year-old has been the heart and sole of the Cardinals pass rush, having eight on the season and being fifth in the NFL. Arizona listed the reason for Sweat missing practice being for Rest, which is good news, but seeing his name on the injury report gave fans a rise in their blood pressure.
Nov 3, 2025; Arlington, Texas, USA; Arizona Cardinals linebacker Josh Sweat (10) celebrates after sacking Dallas Cowboys quarterback Dak Prescott (4) in the second half at AT&T Stadium. Mandatory Credit: Jerome Miron-Imagn Images
Full Cardinals vs. 49ers injury report:
Running back Bam Knight has been limited in back-to-back practice with an ankle injury, leading him to be questionable for Sunday’s game. Fellow running backs Emari Demercado and Michael Carter could be expected to step up and replace Knight if need be, as the run game has been by committee for the offense all season.
Cornerback Max Melton missed last week’s game with a concussion, but was seen with a yellow non-contact jersey on and has been limited the last two days. A fellow player that missed Week 10 was linebacker Mack Wilson Sr., who will remain out this Sunday due to a ribs injury. Backup rookie linebacker Cody Simon will be expected to start for a second straight week, after a forgettable first start last week.
Arizona Cardinals linebacker Mack Wilson Sr. (2) celebrates a defensive stop against the Tennessee Titans at State Farm Stadium in Glendale on Oct. 5, 2025.
Many defensive starters for the Cardinals will be out, which spells trouble with a returning San Francisco 49ers quarterback Brock Purdy under center. The Arizona native has great success against his hometown team. The defense could be due for a repeat performance from last week with the amount of injuries sidelining critical defensive starters.
What Brock Purdy’s return means for Cardinals in Week 11 vs. 49ers
*Get the BEST Phoenix sports insider information, and exclusive content. SIGN UP HERE to unlock our premium content!*
Reporter Tanner Tortorella covers general assignment for Burn City Sports. You can follow him on his X account, @TannerTSports
